Publications

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plastic-degrading enzymes, ancestral sequence reconstruction, protein landscape analysis, biomathematics, protein characterization, protein engineering, protein evolution Dana Matthews plastic-degrading enzymes, ancestral sequence reconstruction, protein landscape analysis, biomathematics, protein characterization, protein engineering, protein evolution Dana Matthews

Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape

Vanessa Vongsouthi, Rosemary Georgelin, Dana S Matthews, Jake Saunders, Brendon M Lee, Jennifer Ton, Adam M Damry, Rebecca L Frkic, Matthew A Spence, Colin J Jackson

Ancestral reconstruction of polyethylene terephthalate degrading cutinases reveals a rugged and unexplored sequence-fitness landscape

Science Advances, 2025

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biomathematics, protein landscape analysis, protein evolution, machine learning Dana Matthews biomathematics, protein landscape analysis, protein evolution, machine learning Dana Matthews

Computational and Experimental Exploration of Protein Fitness Landscapes: Navigating Smooth and Rugged Terrains

Mahakaran Sandhu, John Z Chen, Dana S Matthews, Matthew A Spence, Sacha B Pulsford, Barnabas Gall, Joe A Kaczmarski, James Nichols, Nobuhiko Tokuriki, Colin J Jackson

Computational and Experimental Exploration of Protein Fitness Landscapes: Navigating Smooth and Rugged Terrains

Biochemistry, 2025

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A full list of publications can be found on Google Scholar: