Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors

ancestral sequence reconstructiondeep mutational scanningprotein evolutionepistasis analysis
Written By Dana Matthews

Anthony T Meger, Matthew A Spence, Mahakaran Sandhu, Dana S Matthews, Jackie Chen, Colin J Jackson and Srivatsan Raman

Rugged fitness landscapes minimize promiscuity in the evolution of transcriptional repressors

Cell Systems, 2024

Dana Matthews
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Identification and Characterization of a Bacterial Periplasmic Solute Binding Protein That Binds l-Amino Acid Amides
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